Modafinil and Adrafinil are both popularmodern stimulant drugs well known for boosting the brainpower while also banishing sleepiness and fatigue. The two medications can be obtained in pharmaceuticals not to mention that you can also buy cheap Modafinil online. Though the two substances are related and virtually produces the same effects, they also exhibit some significant differences. Well, here is a side by side comparison of Adrafinil and Modafinil that can help you differentiate between the two.
The similarity between Modafinil and Adrafinil
Let’s start with the similarities given that the two have the same mechanisms of action, and they portray similar benefits and effects.
Mechanism of action– When it comes to the mechanism of action, both Modafinil and Adrafinil activate neurons in the hypothalamus and amygdala thus increasing the output orexin/hypocretin system of the brain, which is primarily responsible for wakefulness. The action also uplifts the levels of histamine and norepinephrine, which contributes to alertness and at the same time raise the availability of glutamate. Glutamate is a valuable excitatory neurotransmitter that is critical to the memory, general cognition, and executive function.
Adrafinil and Modafinil also raise the amount of dopamine available for use in the brain. Dopamine is a neurotransmitter that builds the pressure response, and its increased availability elevates mood and increases alertness.
Benefits and Effects– both drugs are effective in increasing alertness, promoting wakefulness, delaying the onset of fatigue, inhibiting the drive to sleep and reducing the perception of tiredness.
Modafinil and Adrafinil have also been proved to create a measurable improvement in cognitive abilities such as increasing working memory and fluid intelligence, improving pattern recognition, spatial and episodic memory, executive function and performance tasks that require ahigher level of thinking.
The Differences between Adrafinil and Modafinil
Potency and dosage– Modafinil is more potent than Adrafinil, and lower doses are needed to get the same degree of effectiveness. The difference occurs because not all Adrafinil is converted to Modafinil. A typical therapeutic dose of Modafinil ranges from 100mg to 200mg while the average dosages for Adrafinil are 300mg to 600mg.
Onset, Half-life, the effectiveness duration– Modafinil acts more quickly than Adrafinil. Modafinil is at the peak levels in the blood within 60-90 minutes while Adrafinil can take even an hour more to reach the peak levels. The half-life of Modafinil can be up to 4 hours while that of Adrafinil can last up to 5 hours.
Toxicity– Adrafinil has to be metabolized in the liver, and hence it has some potential toxicity for prolonged use
Cost– Adrafinil costs less than Modafinil, and it can be widely available at a fraction of thecost of Modafinil. Modafinil can cost over $300 for a 20-tablet prescription in the US depending on the pharmacy you use.
Where can I buy Modafinil?
Modafinil can be obtained from any localpharmacy depending on where you are located. However, there are some online pharmacies where you can buy cheap Modafinil from the comfort of your home. Buying Modafinil online is pretty cheap plus it saves time. If you want to get order Modafinil online, you just have to go to the website of the online Pharmacy you fancy and make your modafinil order online. Talking of online pharmacies, Afinil express is one of the best online pharmacies where you can buy cheap Modafinil and get it shipped to you within a few days whilst saving you a lot on your pill orders.