Liver transplantation: Function, symptoms, and complication of it


Hepatic transplantation or liver transplantation is one of the replacements of the injured liver with the healthy liver of another person. It is a treatment procedure of end-stage liver disease and critical liver failure. The surgical procedure of liver is very complex where people need careful harvesting of the donor organ. It is a probable treatment for acute or enduring conditions which can be a cause of irreversible liver dysfunction.

The function of the liver: Liver is one of the vital organs of our body which serves several critical functions like metabolism of toxins, remove degradation products from a normal body and synthesize the protein and enzymes of the body. Transplantation is needed when the liver is affected by several diseases like an acute liver failure or chronic liver failure. Many quality liver transplant hospitals in India are available with the best and accurate technique for the treatment purpose.

  1. Acute Liver Failure

Acute liver failure, also identified as the fulminant hepatic failure it occurs when any healthy liver suffering enormous injury and as a result resulting some clinical signs and symptoms are of liver insufficiency.

  1. Chronic liver failure

The liver has a capability of repairing its own injury. However, some repeated injury and repair, can blemishes the liver permanently. At the end stage of damaging is called as cirrhosis. Liver transplantation is necessary for the liver failure purpose for permanently curing of this disease.

Sign and symptoms of a liver problem:

  • Gastrointestinal bleeding: When the liver becomes increasingly damaged and the resistance of the portal blood flow increased pressure on the portal venous system. Then this portal hypertension needs alternative routes for returning the blood to the heart. Small veins are available through the abdomen and outside of the liver. This wall will enlarge when the blood flow increased. This is a life threating situation when people need liver transplantation surgery.
  • Fluid retention: At this condition, the proteins flowing in the bloodstream, including albumin the pressure rise on the liver and it gets injured.
  • Encephalopathy: For clearing ammonia and other toxins from the blood some substance accumulate inside body and people reached into a coma.
  • Jaundice: The degradation of hemoglobin in the liver is the cause of Jaundice. If any people attack by Jaundice several times then they suffer liver failure.

Some complication of liver transplantation:

After the full process of liver transplantation graft rejection is one of the common risks which occurs. Several abnormal liver functions like ammonia level, prothrombin time, bilirubin level, albumin concentration and abnormal blood glucose. Some physical problem also occurs in this situation those are encephalopathy, jaundice, bruising and bleeding tendency. Three main type of graft rejection is acute rejection, hyperacute rejection, and chronic rejection. Before liver transplantation, various type of liver support therapy is needed.

Conclusion: The cause of the liver problem are viral hepatitis, Alcoholic liver disease, metabolic liver disease, Autoimmune Liver Disease, Genetic Liver Disease, Vascular Liver Disease, and Hepatocellular Carcinoma. People who are suffering the major problem of liver make a liver transplantation by consulting with a well-skilled doctor with you.